Work is a fundamental part of life for adults with and without disabilities. Work is also an essential path to economic self-sufficiency and financial stability. At a systems level, the LEAD Center’s work increases knowledge and capacity in seven key areas: customized employment, retention and return-to-work, self-employment, economic advancement, funding long-term supports, universal design and cross-system collaboration. The Workforce Innovation and Opportunity Act (WIOA) creates new opportunities for job seekers with disabilities in the workforce system. The LEAD Center’s work supports partnerships, capacity-building and the leveraging of resources to ensure the successful inclusion of people with disabilities in receiving services and achieving outcomes.